EVALUATION OF THE ANTIMICROBIAL ACTIVITY OF RHODIOLA ROSEA, A TRADITIONAL MEDICINAL PLANT
Wafa Zeidan, Sweta Sharma, Christine Case.
Skyline College, San Bruno, CA.
Rhodiola rosea, commonly called golden root, is a native plant of the circumpolar soils. R. rosea is used in traditional Native American medicine to treat intestinal disorders and tuberculosis. The traditional use suggests that the plant has antibacterial components. Our purpose is to test the hypothesis that R. rosea is antimicrobial and to identify its specific antimicrobial compounds. A commercial alcohol-free root extract was mixed with water, 100% ethyl acetate, 100% methanol, and 95% ethanol. These extracts were screened against bacteria and fungi in agar diffusion assays to determine antimicrobial activity. The ethyl acetate and aqueous extracts inhibited Staphylococcus aureus, Escherichia coli and Mycobacterium phlei bacteria, but did not inhibit Penicillium notatum or Candida albicans fungi. The minimum bactericidal concentration against S. aureus is 0.063 µL/µL, while E. coli was inhibited but not killed at 0.125 µL/µL. The extract does not cause cell lysis. Characterization of the antibacterial properties is in progress. We conclude that R. rosea has antimicrobial properties and may provide source material for a new antimicrobic.